Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963860 | 0.86 | KMT2A (0.44) | ACHEMEN1KMT2AMAOAPYCR1 | |
| SCHEMBL24923420 | 0.82 | SLC6A4 (0.46) | SLC6A4MAOBACHECACNA1B | |
| SCHEMBL21964003 | 0.80 | MEN1 (0.39) | MEN1KMT2APOLB | |
| SCHEMBL21963920 | 0.79 | KCNH2 (0.39) | ACHEMEN1KMT2A | |
| SCHEMBL21964039 | 0.78 | KMT2A (0.57) | MAOBACHEMEN1KMT2AMAOA | |
| SCHEMBL22010475 | 0.78 | KMT2A (0.48) | ACHEMEN1KMT2APYCR1 | |
| SCHEMBL22010754 | 0.78 | CACNA1B (0.43) | SLC6A4CACNA1B | |
| Hydrochloric Acid SCHEMBL28623346 | 0.77 | CACNA1B (0.42) | SLC6A4CACNA1B | |
| Hydrochloric Acid SCHEMBL31033325 | 0.77 | CACNA1B (0.42) | SLC6A4CACNA1B | |
| SCHEMBL21963797 | 0.76 | LMNA (0.41) | ACHEKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272302-A | Antibiotic compounds, process for their manufacture, pharmaceutical compositions containing them and their use | 德彪药业国际股份公司 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |