Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21964039 | 0.86 | KMT2A (0.57) | KMT2AMEN1ACHESMPD1BCHE | |
| SCHEMBL21963860 | 0.81 | KMT2A (0.44) | KMT2AMEN1ACHESMPD1BCHE | |
| SCHEMBL22010476 | 0.78 | SLC6A4 (0.42) | KMT2AMEN1ACHEPYCR1 | |
| SCHEMBL21963733 | 0.78 | KMT2A (0.46) | KMT2AMEN1ACHESMPD1BCHE | |
| SCHEMBL21963819 | 0.76 | KMT2A (0.48) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL21964003 | 0.76 | MEN1 (0.39) | KMT2AMEN1TSHRKDM4EALDH1A1 | |
| SCHEMBL21963920 | 0.74 | KCNH2 (0.39) | KMT2AMEN1ACHEBCHE | |
| SCHEMBL24923421 | 0.73 | LOXL2 (0.34) | — | |
| SCHEMBL4611890 | 0.71 | PYCR1 (0.69) | KMT2AMEN1ACHESMPD1BCHE | |
| SCHEMBL29958539 | 0.68 | HTR2C (0.34) | KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272302-B | Antibiotic compound, method for producing same, pharmaceutical composition containing same, and use thereof | 德彪药业国际股份公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-113272302-A | Antibiotic compounds, process for their manufacture, pharmaceutical compositions containing them and their use | 德彪药业国际股份公司 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |