Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18007608 | 0.78 | PARP1 (0.37) | PARP1 | |
| SCHEMBL18378490 | 0.78 | MAPT (0.34) | PARP1 | |
| SCHEMBL24295490 | 0.74 | PTGS1 (0.33) | PARP1 | |
| SCHEMBL21892961 | 0.74 | MAPT (0.38) | PARP1 | |
| SCHEMBL19869242 | 0.74 | NLRP3 (0.33) | PARP1 | |
| SCHEMBL20681027 | 0.73 | MAPT (0.33) | ALDH1A1 | |
| SCHEMBL28598200 | 0.73 | PARP1 (0.46) | PARP1ALDH1A1 | |
| SCHEMBL20684694 | 0.73 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL18007538 | 0.70 | PARP1 (0.32) | PARP1 | |
| SCHEMBL20692209 | 0.69 | NLRP3 (0.45) | PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102098-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |