SCHEMBL22011359

SCHEMBL22011359

O=C(O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)CCCCCCC(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc(O)c(I)c1)NC(=O)CCC(C(=O)O)N1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.64
▸ ALB P02768 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23862416 1.00 FOLH1 (0.64) FOLH1ALB
SCHEMBL31391930 1.00 FOLH1 (0.64) FOLH1ALB
SCHEMBL23862408 1.00 FOLH1 (0.64) FOLH1ALB
SCHEMBL23252352 1.00 FOLH1 (0.64) FOLH1ALB
SCHEMBL26382169 1.00 FOLH1 (0.64) FOLH1ALB
SCHEMBL21901407 0.98 FOLH1 (0.61) FOLH1ALB
SCHEMBL20283295 0.97 FOLH1 (0.66) FOLH1ALB
SCHEMBL25138620 0.96 ALB (0.62) FOLH1ALB
SCHEMBL20180903 0.96 ALB (0.62) FOLH1ALB
SCHEMBL23862423 0.96 ALB (0.62) FOLH1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023239829-A2 SYSTEMS AND METHODS FOR ASSESSING DISEASE BURDEN AND PROGRESSION PROGENICS PHARMACEUTICALS, INC. (US) 2023-12-14 — — WO disclosed
US-20230302164-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-09-28 — — US disclosed
US-20230277698-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2023-09-07 — — US disclosed
US-20230173112-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-06-08 — — US disclosed
US-11657508-B2 Systems and methods for platform agnostic whole body image segmentation EXINI DIAGNOSTICS AB (SE) 2023-05-23 — — US disclosed
US-20230122957-A1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY Technische Universität München (DE) 2023-04-20 — — US disclosed
US-10980901-B2 Treatment of PMSA expressing cancers THE EUROPEAN ATOMIC ENERGY COMMUNITY (EURATOM), REPRESENTED BY THE EUROPEAN COMMISSION (BE) 2021-04-20 — — US disclosed
US-20200357521-A1 NETWORK FOR MEDICAL IMAGE ANALYSIS, DECISION SUPPORT SYSTEM, AND RELATED GRAPHICAL USER INTERFACE (GUI) APPLICATIONS CITIZENS BANK, N.A. 2020-11-12 — — US disclosed
US-20200297876-A1 PSMA ligands for imaging and endoradiotherapy Technische Universität München (DE) 2020-09-24 — — US disclosed
US-10762993-B2 Network for medical image analysis, decision support system, and related graphical user interface (GUI) applications PROGENICS PHARMACEUTICALS, INC. (US) 2020-09-01 — — US disclosed
US-10665346-B2 Network for medical image analysis, decision support system, and related graphical user interface (GUI) applications PROGENICS PHARMACEUTICALS, INC. (US) 2020-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230122957-A1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY KLK3, FOLH1, EEA1 FOLH1 2/4885ALB 1225/4885
US-20230173112-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy PSMA1, PSMA2, FOLH1 FOLH1 3/4885ALB 948/4885
US-11657508-B2 Systems and methods for platform agnostic whole body image segmentation HTR3D, SSTR3, ERBB3 FOLH1 709/4885ALB 336/4885
US-20200297876-A1 PSMA ligands for imaging and endoradiotherapy KLK3, FOLH1, EEA1 FOLH1 2/4885ALB 1225/4885
US-20230277698-A1 SILICON-CONTAINING LIGAND COMPOUNDS KLK3, SHBG, SELPLG FOLH1 8/4885ALB 1141/4885
US-20230302164-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy PSMA1, PSMA2, FOLH1 FOLH1 3/4885ALB 1065/4885
US-10980901-B2 Treatment of PMSA expressing cancers PMS2, GNRHR, MC5R FOLH1 4/4885ALB 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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