SCHEMBL22011548

SCHEMBL22011548

c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3c4sc5ccccc5c4c4c(ccc5sc6ccccc6c54)c32)cc1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPT P10636 3/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TP53 P04637 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24171454 0.99 KDM4E (0.38) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL22011429 0.90 ATM (0.39) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL22011541 0.89 TP53 (0.32) MAPTRXFP1TP53
SCHEMBL24171789 0.88 KDM4E (0.38) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL24172319 0.88 KDM4E (0.36) KDM4EATML3MBTL1TP53
SCHEMBL17246535 0.86 ATM (0.45) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL18119116 0.85 ATM (0.49) KDM4EATML3MBTL1MAPTHSD17B10
SCHEMBL17246613 0.84 ATM (0.43) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL17406209 0.84 ATM (0.38) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL17405869 0.84 ATM (0.38) KDM4EATML3MBTL1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-01-06 US disclosed
WO-2020099307-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES ZYX, RER1, AOC2 KDM4E 1792/4885ATM 1787/4885L3MBTL1 2301/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 KDM4E 1792/4885ATM 1787/4885L3MBTL1 2301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.