Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23481834 | 0.86 | GLA (0.33) | ABL1CRHR1POLB | |
| SCHEMBL25033784 | 0.84 | EPHX2 (0.33) | ABL1CRHR1POLBMEN1KMT2A | |
| SCHEMBL21892909 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL21893002 | 0.76 | ALDH1A1 (0.34) | SMN1; SMN2 | |
| SCHEMBL20692424 | 0.76 | — | — | |
| SCHEMBL20692429 | 0.76 | ALDH1A1 (0.34) | SMN1; SMN2 | |
| SCHEMBL26018859 | 0.76 | FPR2 (0.30) | — | |
| SCHEMBL25034232 | 0.76 | CNR2 (0.31) | — | |
| SCHEMBL30244067 | 0.76 | ALDH1A1 (0.32) | POLBSMN1; SMN2 | |
| SCHEMBL30244040 | 0.76 | ALDH1A1 (0.32) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |