Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020357 | 0.88 | LOXL2 (0.31) | CA2CA12CA1CA9CA14 | |
| SCHEMBL21963203 | 0.86 | LOXL2 (0.30) | CA2CA12CA1CA9CA14 | |
| SCHEMBL22020358 | 0.85 | CA2 (0.36) | CA2CA12CA1CA9CA14 | |
| SCHEMBL22020356 | 0.80 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL22020743 | 0.76 | LOXL2 (0.30) | CA2CA12CA1CA9CA14 | |
| SCHEMBL22012428 | 0.76 | — | — | |
| SCHEMBL25033903 | 0.75 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL21962102 | 0.75 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL25034209 | 0.75 | LOXL2 (0.32) | LOXL2 | |
| SCHEMBL30276705 | 0.75 | LOXL2 (0.32) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |