Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23481706 | 0.83 | L3MBTL1 (0.38) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL25033760 | 0.82 | L3MBTL1 (0.37) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL21962721 | 0.79 | ALDH1A1 (0.41) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL22002771 | 0.78 | L3MBTL1 (0.35) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL22012481 | 0.77 | POLB (0.40) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL22013537 | 0.77 | MEN1 (0.54) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL22705075 | 0.72 | KMT2A (0.42) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL22013594 | 0.70 | ALDH1A1 (0.41) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL24592537 | 0.69 | ALDH1A1 (0.37) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL22905486 | 0.69 | ALDH1A1 (0.39) | L3MBTL1POLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |