Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197845 | 0.89 | KCNA5 (0.47) | KCNA5CYP19A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2199166 | 0.84 | KCNA5 (0.50) | KCNA5GPBAR1CYP19A1PTGS1PTGS2 | |
| SCHEMBL2196368 | 0.84 | CYP2A6 (0.34) | KCNA5CYP19A1PTGS1PTGS2HTR7 | |
| SCHEMBL12211556 | 0.84 | ATM (0.44) | GPBAR1CYP19A1PTGS2KMT2AATM | |
| SCHEMBL2197727 | 0.83 | KCNA5 (0.48) | KCNA5PTGS1PTGS2KMT2AATM | |
| SCHEMBL2195323 | 0.83 | KCNA5 (0.53) | KCNA5PTGS1PTGS2HTR7PLK1 | |
| SCHEMBL13267947 | 0.82 | KCNA5 (0.45) | KCNA5PLK1TDO2SMN1; SMN2 | |
| SCHEMBL12211391 | 0.82 | KCNA5 (0.45) | KCNA5PTGS1PTGS2KMT2AATM | |
| SCHEMBL2198088 | 0.79 | KCNA5 (0.43) | KCNA5CYP19A1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2199596 | 0.79 | KCNA5 (0.43) | KCNA5CYP19A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | claimed |
| US-20100179059-A1 | Fungicidal Mixtures | BASF SE (DE) | 2010-07-15 | — | — | US | claimed |
| EP-2170071-A2 | FUNGICIDAL MIXTURES | BASF SE (DE) | 2010-04-07 | — | — | EP | claimed |
| WO-2008148859-A2 | FUNGICIDAL MIXTURES | BASF SE (DE) | 2008-12-11 | — | — | WO | claimed |
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2008-07-10 | — | — | US | claimed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | claimed |
| EP-1794167-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | Syngenta Limited (GB) | 2007-06-13 | — | — | EP | claimed |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2006-04-06 | — | — | US | claimed |
| WO-2006031631-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2006-03-23 | — | — | WO | claimed |
| WO-2013011010-A1 | FUNGIZIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013007550-A1 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-17 | — | — | WO | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-7338967-B2 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2008-03-04 | — | — | US | disclosed |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | SYNGENTA LIMITED (GB) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | CYP4X1, CYP51A1, CYP3A7 | KCNA5 850/4885GPBAR1 2958/4885CYP19A1 19/4885 |
| US-20100179059-A1 | Fungicidal Mixtures | ARSA, AADAC, TYR | KCNA5 127/4885GPBAR1 2742/4885CYP19A1 1523/4885 |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | CYP4X1, CYP51A1, CYP3A7 | KCNA5 760/4885GPBAR1 2998/4885CYP19A1 21/4885 |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | CYP4Z1, CYP4X1, AGXT | KCNA5 1858/4885GPBAR1 2523/4885CYP19A1 598/4885 |
| US-20060073971-A1 | Substituted isoxazoles as fungicides | CYP4X1, CYP51A1, CYP3A7 | KCNA5 750/4885GPBAR1 3841/4885CYP19A1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.