Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.70 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.70 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.70 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cgs-15943 SCHEMBL1906971 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL22013575 | 0.82 | ADORA3 (0.74) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL22013573 | 0.82 | CSNK1A1 (1.00) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| Cgs-15943 SCHEMBL29372704 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL22013580 | 0.82 | ADORA2A (0.70) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL24209870 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL22013611 | 0.80 | ADORA3 (0.70) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL8281286 | 0.76 | ADORA3 (0.65) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL22013574 | 0.75 | ADORA3 (0.82) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 | |
| SCHEMBL24210275 | 0.74 | ADORA3 (0.63) | ADORA3ADORA2AADORA2BADORA1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017524-A1 | ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS | THE BROAD INSTITUTE, INC. (US) | 2022-01-20 | — | — | US | disclosed |
| WO-2020102506-A1 | ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS | THE BROAD INSTITUTE, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017524-A1 | ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS | AHR, ESRRA, AR | ADORA3 25/4885ADORA2A 14/4885ADORA2B 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.