Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 3/20 | 1.00 |
| ▸ | CSNK1D | P48730 | 3/20 | 1.00 |
| ▸ | CSNK1E | P49674 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.74 |
| ▸ | GMNN | O75496 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | THPO | P40225 | 1/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.74 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cgs-15943 SCHEMBL29372704 | 0.85 | ADORA3 (1.00) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL22013575 | 0.85 | ADORA3 (0.74) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| Cgs-15943 SCHEMBL1906971 | 0.85 | ADORA3 (1.00) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL24209870 | 0.83 | ADORA3 (0.71) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL22013580 | 0.82 | ADORA2A (0.70) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL22013571 | 0.82 | ADORA3 (0.70) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL22013611 | 0.82 | ADORA3 (0.70) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL8281286 | 0.79 | ADORA3 (0.65) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL22013574 | 0.78 | ADORA3 (0.82) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A | |
| SCHEMBL24210275 | 0.77 | ADORA3 (0.63) | CSNK1A1CSNK1DCSNK1EADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102506-A1 | ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS | THE BROAD INSTITUTE, INC. (US) | 2020-05-22 | — | — | WO | disclosed |