Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 8/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.40 |
| ▸ | MELK | Q14680 | 4/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013253 | 0.82 | MAP4K4 (0.45) | MAP4K4P2RX7 | |
| SCHEMBL23837007 | 0.79 | LRRK2 (0.45) | MAP4K4PTPN11 | |
| SCHEMBL22013660 | 0.79 | MAP4K4 (0.42) | MAP4K4P2RX7 | |
| SCHEMBL23837037 | 0.79 | MELK (0.45) | MAP4K4P2RX7MELK | |
| SCHEMBL23836975 | 0.79 | MAP4K4 (0.41) | MAP4K4P2RX7MELK | |
| SCHEMBL22013614 | 0.78 | MAP4K4 (0.47) | MAP4K4P2RX7 | |
| SCHEMBL23837028 | 0.78 | MAP4K4 (0.47) | MAP4K4P2RX7 | |
| SCHEMBL22013266 | 0.77 | MAP4K4 (0.43) | MAP4K4P2RX7 | |
| SCHEMBL23836958 | 0.76 | MAP4K4 (0.37) | MAP4K4P2RX7MELK | |
| SCHEMBL22013114 | 0.76 | MAP4K4 (0.37) | MAP4K4P2RX7MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882247-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-09-22 | — | — | EP | disclosed |