Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508568 | 0.77 | TSHR (0.50) | CHRM3KDM4EPOLBTSHRNAAA | |
| SCHEMBL22020343 | 0.75 | KDM4E (0.36) | CHRM3KDM4EPOLBTSHRNAAA | |
| SCHEMBL21962731 | 0.74 | CA2 (0.40) | KDM4EPOLBTSHRHTTSMN1; SMN2 | |
| SCHEMBL21962733 | 0.74 | CA2 (0.40) | KDM4EPOLBTSHRHTTSMN1; SMN2 | |
| SCHEMBL22020345 | 0.74 | KDM4E (0.38) | CHRM3KDM4EPOLBTSHRNAAA | |
| SCHEMBL9108156 | 0.73 | TSHR (0.54) | KDM4EPOLBTSHRNAAAHTT | |
| SCHEMBL28671879 | 0.71 | ESR1 (0.41) | CHRM3TSHRSMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL28671877 | 0.71 | ESR1 (0.41) | CHRM3TSHRSMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL31022642 | 0.71 | TSHR (0.47) | CHRM3KDM4EPOLBTSHRNAAA | |
| SCHEMBL21611833 | 0.71 | TSHR (0.47) | KDM4EPOLBTSHRNAAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |