Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962733 | 0.89 | CA2 (0.40) | KDM4EPOLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL21962731 | 0.89 | CA2 (0.40) | KDM4EPOLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL22012717 | 0.83 | HTT (0.32) | KDM4EPOLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL25033767 | 0.82 | KDM4E (0.33) | KDM4EPOLB | |
| SCHEMBL24978358 | 0.82 | KDM4E (0.30) | KDM4EPOLB | |
| SCHEMBL22012978 | 0.82 | HDAC3 (0.33) | KDM4EPOLBHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21962380 | 0.82 | KDM4E (0.33) | KDM4EPOLB | |
| SCHEMBL22020344 | 0.81 | PSMB5 (0.32) | KMT2AMEN1 | |
| SCHEMBL22020345 | 0.75 | KDM4E (0.38) | KDM4EPOLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL22013697 | 0.75 | CHRM3 (0.43) | KDM4EPOLBHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20160248025-A1 | Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2016-08-25 | — | — | US | disclosed |