Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614773 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL28611695 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL31320227 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL22013497 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL22013852 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29397236 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL15840598 | 0.70 | ALDH1A1 (0.59) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL22013244 | 0.62 | ALDH1A1 (0.71) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL15840763 | 0.62 | ALDH1A1 (0.62) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL31320231 | 0.62 | ALDH1A1 (0.70) | ALDH1A1KMT2ARAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880205-B1 | MADRASIN-DERIVATIVE COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER | ROUSSY INST GUSTAVE (FR) | 2023-08-30 | — | — | EP | disclosed |
| WO-2020099650-A1 | MADRASIN-DERIVATIVE COMPOUNDS, COMPOSITION AND USES THEREOF FOR TREATING CANCER | INSTITUT GUSTAVE ROUSSY (FR) | 2020-05-22 | — | — | WO | disclosed |