⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629263 | 0.72 | CA12 (0.51) | — | |
| SCHEMBL8627858 | 0.72 | CA1 (0.38) | — | |
| SCHEMBL629408 | 0.70 | CA1 (0.62) | — | |
| SCHEMBL8632031 | 0.67 | NPSR1 (0.42) | — | |
| SCHEMBL8627364 | 0.67 | — | — | |
| SCHEMBL393631 | 0.65 | MAPT (0.44) | — | |
| SCHEMBL989627 | 0.65 | — | — | |
| SCHEMBL7209005 | 0.64 | — | — | |
| SCHEMBL564354 | 0.64 | — | — | |
| SCHEMBL2629359 | 0.64 | SMN1; SMN2 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890942-B2 | Acyl sulfonamides as inhibitors of HIV integrase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-05-10 | — | — | US | claimed |
| US-20050004232-A1 | Acyl sulfonamides as inhibitors of HIV integrase | BRISTOL-MYERS SQUIBB COMPANY | 2005-01-06 | — | — | US | claimed |
| WO-2004103278-A2 | ACYL SULFONAMIDES AS INHIBITORS OF HIV INTEGRASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-02 | — | — | WO | claimed |
| US-6365603-B1 | FOR THERAPY OF PAIN SUCH AS THE PAIN ASSOCIATED WITH JOINT CONDITIONS SUCH AS RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS, POSTOPERATIVE PAIN, POSTPARTUM PAIN, THE PAIN ASSOCIATED WITH DENTAL CONDITIONS SUCH AS DENTAL CARIES AND GINGIVITIS, ETC. | ZENECA LTD. (GB) | 2002-04-02 | — | — | US | claimed |
| EP-0835246-B1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2001-10-24 | — | — | EP | claimed |
| US-6100258-A | 6-(N-(5-BROMO-2-(2-METHYLPROP-2-EN-1-YLOXY)BENZYL)-N -ETHYLAMINO)-PYRIDAZIN-3-YLCARBOXYLIC ACID, AND OTHER 3,6-DISUBSTITUTED PYRIDAZINE DERIVATIVES OF SPECIFIED FORMULA; RELIEVING PAIN | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | claimed |
| US-5994353-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1999-11-30 | — | — | US | claimed |
| EP-0835246-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1998-04-15 | — | — | EP | claimed |
| WO-1997000863-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1997-01-09 | — | — | WO | claimed |
| US-4933356-A | GLAUCOMA TREATMENT | CORNELL RESEARCH FOUNDATION, INC. (US) | 1990-06-12 | — | — | US | claimed |
| EP-0021176-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-01-18 | — | — | EP | claimed |
| US-4415566-A | ANTIBIOTICS; BACTERIOSTATS; BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DE) | 1983-11-15 | — | — | US | claimed |
| US-4388315-A | TAUTOMERIC PYRIMIDINE DERIVATIVES | BOEHRINGER INGELEHEIM GMBH (DE) | 1983-06-14 | — | — | US | claimed |
| EP-0022494-B1 | BETA-LACTAM-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-02-23 | — | — | EP | claimed |
| EP-0002586-B1 | METHOD FOR REMOVING A HALOGENOACETYL PROTECTIVE GROUP FROM A HALOGENOACETYL AMINO COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | claimed |
| US-4251657-A | Method for removing protective groups | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | claimed |
| EP-0022494-A1 | Beta-lactam-compounds, process for their preparation and therapeutic agents containing them | Dr. Karl Thomae GmbH (DE) | 1981-01-21 | — | — | EP | claimed |
| EP-0021176-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1981-01-07 | — | — | EP | claimed |
| US-4237130-A | DIURETICS, HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-12-02 | — | — | US | claimed |
| EP-0002586-A1 | Method for removing a halogenoacetyl protective group from a halogenoacetyl amino compound | Takeda Chemical Industries, Ltd. (JP) | 1979-06-27 | — | — | EP | claimed |