⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746751 | 0.81 | KDM4E (0.43) | — | |
| SCHEMBL115951 | 0.65 | — | — | |
| SCHEMBL24491066 | 0.65 | — | — | |
| SCHEMBL2201403 | 0.65 | — | — | |
| SCHEMBL629408 | 0.64 | CA1 (0.62) | — | |
| Hydrochloric Acid SCHEMBL29059238 | 0.64 | AGER (0.64) | — | |
| Hydrochloric Acid SCHEMBL28995499 | 0.64 | AGER (0.64) | — | |
| SCHEMBL29043282 | 0.64 | — | — | |
| SCHEMBL2175131 | 0.64 | RAB9A (0.60) | — | |
| SCHEMBL393631 | 0.64 | MAPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083617-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-09-11 | — | — | EP | claimed |
| EP-3083617-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2016-10-26 | — | — | EP | claimed |
| US-9321776-B2 | Isochromene derivatives as phoshoinositide 3-kinases inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-04-26 | — | — | US | claimed |
| WO-2015091685-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-25 | — | — | WO | claimed |
| US-20150166549-A1 | ISOCHROMENE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-18 | — | — | US | claimed |
| US-4136253-A | ANTIBIOTICS | PFIZER INC. (US) | 1979-01-23 | — | — | US | claimed |
| EP-4371986-A2 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2024-05-22 | — | — | EP | disclosed |
| EP-4357344-A2 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2024-04-24 | — | — | EP | disclosed |
| EP-3737667-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-04-03 | — | — | EP | disclosed |
| CN-114555563-A | Substituted pyridazinones as herbicides | 先正达农作物保护股份公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3999494-A2 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| WO-2021009334-A2 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |
| US-20210009530-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |
| US-5616579-A | ADMINISTERING TO MAMMALS TO PREVENT GASTRIC ULCER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0562833-B1 | Anti-ulcer pyridyloxy derivatives, their preparation and uses | SANKYO CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| CN-1081437-A | Antiulcer pyridine oxygen derivative, their preparation method and purposes | SANKYO CO (JP) | 1994-02-02 | — | — | CN | disclosed |
| EP-0562833-A1 | Anti-ulcer pyridyloxy derivatives, their preparation and uses | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4136253-A | ANTIBIOTICS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |