Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CA3 | P07451 | 5/20 | 0.51 |
| ▸ | CA4 | P22748 | 5/20 | 0.51 |
| ▸ | CA6 | P23280 | 5/20 | 0.51 |
| ▸ | CA5A | P35218 | 5/20 | 0.51 |
| ▸ | CA7 | P43166 | 5/20 | 0.51 |
| ▸ | CA9 | Q16790 | 5/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630772 | 0.82 | POLB (0.49) | CA12CA1CA2CA3CA4 | |
| SCHEMBL8627858 | 0.78 | CA1 (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11685658 | 0.74 | MAPT (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL970034 | 0.72 | TSHR (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11327057 | 0.72 | CA12 (0.62) | CA12CA1CA2CA3CA4 | |
| SCHEMBL6248862 | 0.70 | LMNA (0.63) | PKMALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL8631762 | 0.69 | ALDH1A1 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7392391 | 0.66 | SMN1; SMN2 (0.60) | ALDH1A1HPGDHTTMAPTMEN1 | |
| SCHEMBL11685860 | 0.65 | ALDH1A1 (0.48) | ALDH1A1HPGDPOLBL3MBTL1HSD17B10 | |
| Dimethyl Succinate SCHEMBL28054469 | 0.64 | TSHR (1.00) | CA12CA14ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |