Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730572 | 0.86 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL25756238 | 0.84 | TTR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL23803718 | 0.83 | TTR (0.47) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL26586703 | 0.82 | HDAC3 (0.39) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12942074 | 0.81 | BPTF (0.46) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL14081588 | 0.81 | MAPK1 (0.41) | POLBMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL19678485 | 0.81 | HDAC3 (0.38) | TSHRGAAPOLBALDH1A1KDM4E | |
| SCHEMBL26426702 | 0.80 | CHRM1 (0.42) | TSHRGAAMAPTLMNAL3MBTL1 | |
| SCHEMBL21783823 | 0.80 | HTR3A (0.50) | TSHRLMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL21705778 | 0.80 | HDAC3 (0.39) | TSHRPOLBALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306298-B | Application of 2,3, 5-triiodo-benzoyl hydrazine in preparing anti-EV 71 virus medicament | 湖北工业大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-114306298-A | Application of 2,3, 5-triiodo-benzoyl hydrazine in preparation of anti-EV 71 virus drugs | 湖北工业大学 | 2022-04-12 | — | — | CN | disclosed |
| WO-2020099190-A1 | POLYMER FOR LIQUID EMBOLIC AGENTS AND METHOD OF OBTAINING SAME | LVD BIOTECH S. L. (ES) | 2020-05-22 | — | — | WO | disclosed |