Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015042 | 0.82 | DAO (0.36) | DAOMAPTCNR2 | |
| SCHEMBL21962629 | 0.73 | DAO (0.40) | DAOCNR2 | |
| SCHEMBL22014353 | 0.70 | DAO (0.39) | DAOCNR2 | |
| SCHEMBL21962152 | 0.67 | DAO (0.36) | DAO | |
| SCHEMBL16029079 | 0.64 | TNKS2 (0.32) | — | |
| SCHEMBL25067113 | 0.62 | FFAR1 (0.37) | CNR2 | |
| SCHEMBL20919052 | 0.60 | THRA (0.40) | — | |
| SCHEMBL28001408 | 0.59 | MAOB (0.43) | DAO | |
| SCHEMBL23276912 | 0.59 | THRA (0.43) | DAO | |
| SCHEMBL2252275 | 0.58 | CYP4A11 (0.51) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |