Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014415 | 0.78 | NLRP3 (0.43) | NLRP3 | |
| SCHEMBL20698963 | 0.77 | NLRP3 (0.51) | NLRP3 | |
| SCHEMBL23692265 | 0.74 | NLRP3 (0.61) | NLRP3 | |
| SCHEMBL25066964 | 0.73 | NLRP3 (0.38) | NLRP3 | |
| SCHEMBL22014426 | 0.72 | NLRP3 (0.41) | NLRP3 | |
| SCHEMBL25139122 | 0.71 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL19507307 | 0.67 | NLRP3 (0.40) | NLRP3P2RX7 | |
| SCHEMBL29687458 | 0.67 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL20681566 | 0.67 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL24783796 | 0.67 | P2RX7 (0.36) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |