SCHEMBL22015050

SCHEMBL22015050

CCOC(=O)C(=[N+]=NC)C(=O)c1ncco1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.34
FAAH O00519 4/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PKM P14618 1/20 0.33
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
NCEH1 Q6PIU2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21964035 0.85 CES1 (0.36) CES1FAAHALDH1A1NPC1RAB9A
SCHEMBL3229623 0.81 CES1 (0.41) CES1FAAHALDH1A1NPC1RAB9A
SCHEMBL22015067 0.78 MAPT (0.37) ALDH1A1NPC1RAB9APKM
SCHEMBL2422303 0.72 FAAH (0.43) CES1FAAHALDH1A1PKM
SCHEMBL30753499 0.70 FAAH (0.42) CES1FAAHALDH1A1PKMADORA2A
Benzene SCHEMBL30353855 0.69 CES1 (0.43) CES1FAAHALDH1A1PKMHDAC3
SCHEMBL22015495 0.67 CES1 (0.46) CES1FAAHALDH1A1PKMHDAC3
SCHEMBL17853343 0.65 FAAH (0.44) CES1FAAHHDAC3HDAC4HDAC1
SCHEMBL21963668 0.63 MAPT (0.39) ALDH1A1NPC1RAB9APKM
SCHEMBL4152892 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099404-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-05-22 WO disclosed