Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422303 | 0.80 | FAAH (0.43) | CES1FAAHGAAALDH1A1KDM4E | |
| SCHEMBL30753499 | 0.78 | FAAH (0.42) | CES1FAAHGAAALDH1A1KDM4E | |
| SCHEMBL4152892 | 0.77 | — | — | |
| Benzene SCHEMBL30353855 | 0.77 | CES1 (0.43) | CES1FAAHALDH1A1KDM4EKMT2A | |
| SCHEMBL3229623 | 0.77 | CES1 (0.41) | CES1FAAHALDH1A1HDAC3HDAC4 | |
| SCHEMBL13516204 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EMEN1KMT2AHDAC4 | |
| SCHEMBL7367753 | 0.75 | FAAH (0.60) | CES1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL11264225 | 0.73 | SMN1; SMN2 (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL24095817 | 0.73 | FAAH (0.50) | CES1FAAHHDAC3HDAC4HDAC1 | |
| SCHEMBL1505564 | 0.73 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099404-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |