Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19570333 | 0.85 | HTR2A (0.36) | SSTR4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL18407310 | 0.76 | DAO (0.34) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL8404416 | 0.74 | SSTR4 (0.38) | SSTR4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL1289913 | 0.69 | ALDH1A1 (0.45) | SSTR4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL15077047 | 0.68 | GPR139 (0.35) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL23108716 | 0.68 | HDAC8 (0.52) | SSTR4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL12190492 | 0.67 | KDM4E (0.37) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL24410771 | 0.67 | SSTR4 (0.35) | SSTR4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL16256090 | 0.67 | KDM4E (0.39) | SSTR4KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8404406 | 0.66 | PTPN1 (0.39) | SSTR4KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |