Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015379 | 0.76 | SSTR4 (0.54) | SSTR4 | |
| SCHEMBL22015382 | 0.76 | SSTR4 (0.54) | SSTR4KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL22015969 | 0.76 | SSTR4 (0.54) | SSTR4KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL16255883 | 0.75 | SSTR4 (0.47) | SSTR4CYP1A2POLBCYP2C9KDM4E | |
| SCHEMBL16256029 | 0.75 | SSTR4 (0.59) | SSTR4CYP1A2POLBCYP2C9KMT2A | |
| SCHEMBL25804507 | 0.73 | CYP1A2 (0.57) | SSTR4CYP1A2POLBCYP2C9KDM4E | |
| SCHEMBL22015391 | 0.71 | SSTR4 (0.51) | SSTR4KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL22015657 | 0.70 | SSTR4 (0.60) | SSTR4 | |
| SCHEMBL16255854 | 0.70 | SSTR4 (1.00) | SSTR4 | |
| SCHEMBL19724569 | 0.70 | SSTR4 (1.00) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |