Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 11/20 | 0.51 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.31 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015336 | 0.81 | SSTR4 (0.52) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015382 | 0.75 | SSTR4 (0.54) | SSTR4KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL22015379 | 0.75 | SSTR4 (0.54) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL16256091 | 0.74 | SSTR4 (0.45) | SSTR4KDM4ENPSR1NPC1ALDH1A1 | |
| SCHEMBL22015341 | 0.71 | SSTR4 (0.53) | SSTR4KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL22015969 | 0.70 | SSTR4 (0.54) | SSTR4SSTR1KDM4EMAPTRECQL | |
| SCHEMBL8404416 | 0.68 | SSTR4 (0.38) | SSTR4KDM4EMAPTRECQLNPSR1 | |
| SCHEMBL19724582 | 0.68 | SSTR4 (1.00) | SSTR4SSTR1SSTR3 | |
| SCHEMBL22015780 | 0.67 | — | — | |
| SCHEMBL22015257 | 0.63 | SSTR4 (0.35) | SSTR4KDM4EMAPTRECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |