Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015380 | 0.86 | SSTR4 (0.34) | SSTR4LMNAPARP1TNKSTNKS2 | |
| SCHEMBL19570339 | 0.78 | SSTR4 (0.40) | CHEK1MAPTKMT2AATMSSTR1 | |
| SCHEMBL13208507 | 0.77 | AHR (0.46) | CHEK1TRIM24TRIM33AHRKIF11 | |
| SCHEMBL17763202 | 0.74 | AHR (0.43) | CHEK1TRIM24TRIM33AHRKIF11 | |
| SCHEMBL17763199 | 0.74 | EPHX2 (0.38) | CHEK1MAPTKMT2ASSTR1SSTR4 | |
| SCHEMBL22015967 | 0.72 | SSTR4 (0.53) | KMT2ASSTR1SSTR4KDM4EPARP1 | |
| SCHEMBL22015743 | 0.72 | SSTR4 (0.53) | SSTR4MCL1 | |
| SCHEMBL16252673 | 0.70 | SSTR4 (0.68) | SSTR1SSTR4 | |
| SCHEMBL19724371 | 0.70 | SSTR4 (0.68) | SSTR1SSTR4 | |
| SCHEMBL19724792 | 0.70 | SSTR4 (0.68) | SSTR1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |