Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 8/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015377 | 0.86 | CHEK1 (0.40) | SSTR4TNKSPARP1TNKS2LMNA | |
| SCHEMBL19564989 | 0.81 | LMNA (0.34) | SSTR4TNKSPARP1TNKS2LMNA | |
| SCHEMBL17515575 | 0.79 | MAPK10 (0.36) | SSTR4TNKSPARP1TNKS2LMNA | |
| SCHEMBL14158304 | 0.77 | TNKS (0.44) | SSTR4TNKSPARP1TNKS2LMNA | |
| SCHEMBL17754801 | 0.76 | CHEK1 (0.35) | SSTR4TNKSPARP1TNKS2LMNA | |
| SCHEMBL17755286 | 0.76 | SSTR4 (0.38) | SSTR4PARP1 | |
| Hydrochloric Acid SCHEMBL31410063 | 0.75 | SLC6A4 (0.34) | TNKSPARP1TNKS2LMNAFEN1 | |
| SCHEMBL14157298 | 0.74 | MAPK10 (0.37) | LMNAFEN1CFTRMAPK10RIPK1 | |
| SCHEMBL22015378 | 0.72 | SSTR4 (0.54) | SSTR4 | |
| SCHEMBL19724776 | 0.71 | SSTR4 (0.67) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |