Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 9/20 | 0.53 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256086 | 0.75 | SSTR4 (0.47) | SSTR4SSTR1ELANEPARP1TP53 | |
| SCHEMBL22015377 | 0.72 | CHEK1 (0.40) | SSTR4SSTR1PARP1TNKSTNKS2 | |
| SCHEMBL22015743 | 0.71 | SSTR4 (0.53) | SSTR4 | |
| SCHEMBL21778937 | 0.71 | SSTR4 (0.51) | SSTR4SSTR1TP53KDM4E | |
| SCHEMBL19724648 | 0.70 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL19724549 | 0.70 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL16255861 | 0.70 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL18179842 | 0.67 | RAD52 (0.54) | ELANEPARP1TP53TNKSTNKS2 | |
| SCHEMBL22015662 | 0.67 | SSTR4 (0.49) | SSTR4SSTR1MEN1KMT2A | |
| SCHEMBL27393825 | 0.64 | CYP2A6 (0.46) | SSTR4SSTR1ELANEPARP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |