Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019799 | 0.79 | ALOX15 (0.33) | — | |
| SCHEMBL20400506 | 0.76 | CA12 (0.32) | — | |
| SCHEMBL22014776 | 0.75 | SMPD3 (0.36) | SMPD3 | |
| SCHEMBL22011823 | 0.75 | SSTR4 (0.33) | — | |
| SCHEMBL24871872 | 0.75 | — | — | |
| SCHEMBL24871942 | 0.72 | — | — | |
| SCHEMBL22858308 | 0.66 | DRD4 (0.34) | — | |
| SCHEMBL20939716 | 0.65 | SMPD3 (0.35) | SMPD3 | |
| SCHEMBL22309811 | 0.63 | LRRK2 (0.31) | — | |
| SCHEMBL20828043 | 0.63 | LRRK2 (0.42) | SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |