Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26775986 | 1.00 | LRRK2 (0.42) | LRRK2SMPD3MAP3K12 | |
| SCHEMBL26775847 | 1.00 | LRRK2 (0.42) | LRRK2SMPD3MAP3K12 | |
| SCHEMBL15528392 | 0.76 | LRRK2 (0.42) | LRRK2 | |
| SCHEMBL15528190 | 0.76 | LRRK2 (0.42) | LRRK2 | |
| SCHEMBL26644039 | 0.73 | LRRK2 (0.38) | LRRK2 | |
| SCHEMBL16470036 | 0.70 | LRRK2 (0.41) | LRRK2 | |
| SCHEMBL26643625 | 0.66 | HTR1A (0.33) | LRRK2 | |
| SCHEMBL22015524 | 0.63 | SMPD3 (0.32) | SMPD3 | |
| Hydrochloric Acid SCHEMBL20473846 | 0.63 | SMPD3 (0.31) | SMPD3 | |
| SCHEMBL20663913 | 0.62 | MPO (0.46) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119317626-A | Pyrrolidone derivatives as inhibitors of NF- κb-induced kinase | 詹森药业有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2023217851-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF-κB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |
| EP-2844658-B1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | GENENTECH INC (US) | 2019-03-20 | — | — | EP | disclosed |