Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015975 | 0.78 | SSTR4 (0.55) | SSTR4SSTR1 | |
| SCHEMBL22015610 | 0.77 | SSTR4 (0.51) | SSTR4ALDH1A1KDM4ESSTR1CCR4 | |
| SCHEMBL16252856 | 0.77 | SSTR4 (0.49) | SSTR4ALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL22015693 | 0.73 | SSTR4 (0.55) | SSTR4ALDH1A1CYP2C9KDM4ESSTR1 | |
| SCHEMBL19724514 | 0.71 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL16252672 | 0.71 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL8537040 | 0.70 | MEN1 (0.43) | SSTR4ALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL16252885 | 0.69 | SSTR4 (0.70) | SSTR4SSTR1 | |
| SCHEMBL19724400 | 0.69 | SSTR4 (0.70) | SSTR4SSTR1 | |
| SCHEMBL28159924 | 0.69 | ALDH1A1 (0.51) | SSTR4ALDH1A1MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |