Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 8/20 | 0.55 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015664 | 0.85 | KDM4C (0.40) | SSTR4SYKSSTR1KDM4CLMNA | |
| SCHEMBL22015610 | 0.80 | SSTR4 (0.51) | SSTR4SSTR1KDM4EALDH1A1SSTR2 | |
| SCHEMBL16252857 | 0.77 | SSTR4 (0.49) | SSTR4SYKKDM4CKDM4EATM | |
| SCHEMBL22015661 | 0.73 | SSTR4 (0.55) | SSTR4SSTR1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL22015975 | 0.73 | SSTR4 (0.55) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL15902309 | 0.72 | ALDH1A1 (0.44) | SSTR4SYKKDM4CKDM4EATM | |
| SCHEMBL19724468 | 0.71 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL16252668 | 0.71 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL19724364 | 0.71 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL19724366 | 0.69 | SSTR4 (0.70) | SSTR4SSTR1SSTR2SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |