Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 10/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 4/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 4/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015693 | 0.85 | SSTR4 (0.55) | KDM4CSSTR4SSTR1SSTR2SSTR3 | |
| SCHEMBL22015610 | 0.81 | SSTR4 (0.51) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL18538064 | 0.79 | ADORA2A (0.41) | KDM4CSSTR4SSTR1NAMPTADORA2A | |
| SCHEMBL5986727 | 0.74 | GRM4 (0.44) | KDM4CADORA2AADORA2BLMNAGRM4 | |
| SCHEMBL22015661 | 0.69 | SSTR4 (0.55) | SSTR4SSTR1 | |
| SCHEMBL22015383 | 0.69 | SSTR4 (0.55) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015975 | 0.69 | SSTR4 (0.55) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL11804 | 0.68 | ADORA2A (0.63) | KDM4CNAMPTADORA2AADORA2BGRM4 | |
| SCHEMBL22015373 | 0.67 | SSTR4 (0.56) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL18538063 | 0.66 | MEN1 (0.37) | SSTR4NAMPTADORA2AADORA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |