Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furfural SCHEMBL4869864 | 0.97 | ALDH1A1 (0.60) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL5622383 | 0.94 | ALDH1A1 (0.56) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL21383179 | 0.91 | ALDH1A1 (0.53) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL20378730 | 0.88 | ALDH1A1 (0.50) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL4538163 | 0.85 | ALDH1A1 (0.46) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL896784 | 0.80 | ALDH1A1 (0.69) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL23273775 | 0.79 | — | — | |
| Furfural SCHEMBL28226312 | 0.78 | ALDH1A1 (0.67) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL2203874 | 0.77 | ALDH1A1 (0.78) | ALDH1A1POLBTDP1MAPTMEN1 | |
| Furfural SCHEMBL28172662 | 0.77 | ALDH1A1 (0.64) | ALDH1A1POLBTDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050418-A1 | PRODUCTION OF BENZENE DERIVATIVES | RHODIA OPERATIONS (FR) | 2023-02-16 | — | — | US | disclosed |
| EP-4073021-A1 | PRODUCTION OF BENZENE DERIVATIVES | RHODIA OPERATIONS (FR) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021114207-A1 | PRODUCTION OF BENZENE DERIVATIVES | RHODIA OPERATIONS (FR) | 2021-06-17 | — | — | WO | disclosed |
| US-7982046-B2 | Method for the production of functionalized five-ring heterocycles, and use thereof | CHEMETALL GMBH (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20090131685-A1 | Method for the Production of Functionalized Five-Ring Heterocycles, and use thereof | CHEMETALL GMBH (DE) | 2009-05-21 | — | — | US | disclosed |
| EP-1280816-A1 | 19-NORBUFALIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001079256-A1 | 19-NORBUFALIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050418-A1 | PRODUCTION OF BENZENE DERIVATIVES | CBR1, CBR3, BLVRB | ALDH1A1 371/4885POLB 1353/4885TDP1 3168/4885 |
| US-20090131685-A1 | Method for the Production of Functionalized Five-Ring Heterocycles, and use thereof | CYP3A5, CBR3, CYP2A7 | ALDH1A1 965/4885POLB 4488/4885TDP1 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.