Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470000 | 0.85 | KDM4E (0.36) | USP2ESR1KDM4ECA1CA2 | |
| SCHEMBL11070902 | 0.83 | USP2 (0.42) | USP2ESR1KDM4E | |
| SCHEMBL11070906 | 0.83 | USP2 (0.42) | USP2ESR1KDM4E | |
| SCHEMBL18155365 | 0.79 | USP2 (0.36) | USP2ESR1KDM4E | |
| SCHEMBL9470709 | 0.78 | USP2 (0.37) | USP2ESR1KDM4E | |
| SCHEMBL10839629 | 0.78 | USP2 (0.43) | USP2ESR1KDM4E | |
| SCHEMBL22582118 | 0.78 | USP2 (0.43) | USP2ESR1KDM4E | |
| SCHEMBL10662497 | 0.78 | USP2 (0.43) | USP2ESR1KDM4E | |
| SCHEMBL10662507 | 0.78 | USP2 (0.43) | USP2ESR1KDM4E | |
| SCHEMBL20885265 | 0.77 | NAAA (0.39) | USP2ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |