SCHEMBL9470709

SCHEMBL9470709

CC1C(NN)C(=O)N1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
ESR1 P03372 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18155365 0.82 USP2 (0.36) USP2ESR1KDM4E
SCHEMBL22015759 0.78 USP2 (0.41) USP2ESR1KDM4E
SCHEMBL11070902 0.75 USP2 (0.42) USP2ESR1KDM4E
SCHEMBL11070906 0.75 USP2 (0.42) USP2ESR1KDM4E
SCHEMBL22582139 0.74 USP2 (0.31) USP2ESR1KDM4E
SCHEMBL1686983 0.74 FAP (0.30) USP2ESR1KDM4E
SCHEMBL9486743 0.74 FAP (0.30) USP2ESR1KDM4E
SCHEMBL7811433 0.74 FAP (0.30) USP2ESR1KDM4E
SCHEMBL4523110 0.74 FAP (0.30) USP2ESR1KDM4E
SCHEMBL8311599 0.74 FAP (0.30) USP2ESR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5254681-A Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1993-10-19 US disclosed
EP-0411541-A2 Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-02-06 EP disclosed
EP-0411541-A2 Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-02-06 EP disclosed