Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 18/20 | 0.36 |
| ▸ | FPR2 | P25090 | 16/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988738 | 0.80 | FPR1 (0.38) | FPR1FPR2 | |
| SCHEMBL20041965 | 0.79 | FPR1 (0.41) | FPR1FPR2 | |
| SCHEMBL19559530 | 0.70 | FPR1 (0.35) | FPR1FPR2 | |
| SCHEMBL16785337 | 0.69 | PDE4A (0.49) | FPR1FPR2 | |
| SCHEMBL21341994 | 0.69 | HTR2A (0.48) | — | |
| SCHEMBL20177630 | 0.69 | FPR1 (0.38) | FPR1FPR2TAAR1 | |
| SCHEMBL19559455 | 0.69 | PDE4A (0.49) | FPR1FPR2 | |
| SCHEMBL19559481 | 0.69 | FPR1 (0.34) | FPR1FPR2 | |
| SCHEMBL20177492 | 0.69 | TAAR1 (0.35) | FPR1FPR2TAAR1 | |
| SCHEMBL18117758 | 0.69 | FPR1 (0.34) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102643-A1 | SYNTHETIC PROCESSES FOR THE PRODUCTION OF 1-((3S,4R)-4-(2,6-DIFLUORO-4-METHOXYPHENYL)-2-OXOPYRROLIDIN-3-YL)-3-PHENYLUREA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-05-22 | — | — | WO | disclosed |