Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.32 |
| ▸ | CPS1 | P31327 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015871 | 0.79 | FPR1 (0.36) | FPR1FPR2 | |
| SCHEMBL24434524 | 0.73 | FPR1 (0.44) | FPR1FPR2PDK2CHRNB2CHRNA4 | |
| SCHEMBL19559391 | 0.73 | FPR1 (0.45) | FPR1FPR2 | |
| SCHEMBL16785448 | 0.73 | FPR1 (0.45) | FPR1FPR2 | |
| SCHEMBL29955510 | 0.66 | ENPP2 (0.35) | FPR1FPR2PDK2CPS1 | |
| SCHEMBL29434224 | 0.66 | FPR2 (0.58) | FPR1FPR2 | |
| SCHEMBL20996238 | 0.66 | FPR2 (0.58) | FPR1FPR2 | |
| SCHEMBL16785442 | 0.66 | FPR2 (0.58) | FPR1FPR2 | |
| SCHEMBL18106704 | 0.66 | FPR2 (0.56) | FPR1FPR2 | |
| SCHEMBL19988738 | 0.66 | FPR1 (0.38) | FPR1FPR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |