Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12775457 | 0.75 | SSTR4 (0.44) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015342 | 0.73 | SSTR4 (0.50) | SSTR4SSTR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21778937 | 0.72 | SSTR4 (0.51) | SSTR4SSTR1L3MBTL1ALDH1A1 | |
| SCHEMBL16252858 | 0.72 | SSTR4 (0.43) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL89446 | 0.70 | SMN1; SMN2 (0.58) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22015610 | 0.69 | SSTR4 (0.51) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015377 | 0.68 | CHEK1 (0.40) | SSTR4SSTR1KMT2AMEN1POLB | |
| Ammonia Solution, Strong SCHEMBL27658861 | 0.67 | SMN1; SMN2 (0.56) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL22015967 | 0.67 | SSTR4 (0.53) | SSTR4SSTR1KMT2AMEN1 | |
| SCHEMBL22015743 | 0.67 | SSTR4 (0.53) | SSTR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |