Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 6/20 | 0.32 |
| ▸ | CNR2 | P34972 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690184 | 0.89 | ZDHHC20 (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL24690197 | 0.86 | ZDHHC20 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL10964054 | 0.86 | ALDH1A1 (0.39) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL12314771 | 0.83 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL22490941 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL24486557 | 0.83 | ZDHHC20 (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL17175306 | 0.83 | ALDH1A1 (0.37) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL25469140 | 0.81 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL19472470 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29804873 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212574-A1 | REDOX CURING DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2020-10-22 | — | — | WO | disclosed |
| WO-2020099518-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY DETREY GMBH (DE) | 2020-05-22 | — | — | WO | disclosed |