Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10318170 | 0.82 | CYP2C9 (0.66) | CYP2C9MAPK14POLBCYP2D6SMN1; SMN2 | |
| SCHEMBL2198787 | 0.82 | MAPK14 (0.53) | CYP2C9MAPK14POLBCYP2D6LMNA | |
| SCHEMBL2739971 | 0.80 | POLB (0.69) | CYP2C9MAPK14POLBCYP2D6LMNA | |
| SCHEMBL2196637 | 0.80 | HPGD (0.51) | MAPK14POLBLMNASMN1; SMN2TSHR | |
| SCHEMBL10318171 | 0.80 | POLB (0.69) | CYP2C9MAPK14POLBCYP2D6LMNA | |
| SCHEMBL2198449 | 0.78 | HPGD (0.64) | SMN1; SMN2TSHRKMT2AALDH1A1 | |
| SCHEMBL2195108 | 0.78 | HPGD (0.55) | MAPK14LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12459935 | 0.78 | CD274 (0.79) | CYP2C9CYP2D6LMNASMN1; SMN2TSHR | |
| SCHEMBL5840749 | 0.76 | POLB (0.69) | CYP2C9MAPK14POLBCYP2D6LMNA | |
| SCHEMBL22823029 | 0.76 | SMN1; SMN2 (0.70) | CYP2C9POLBCYP2D6SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | CYP2C9 1130/4885MAPK14 697/4885POLB 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.