SCHEMBL2201619

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2199582	0.93	BRD4 (0.40)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2197274	0.86	CDC7 (0.57)	BRD4CDC7MEN1IKBKBJAK2
	SCHEMBL12509725	0.86	BRD4 (0.44)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2198480	0.86	NPC1 (0.46)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2198095	0.86	CDC7 (0.57)	BRD4CDC7
	SCHEMBL12423887	0.86	BRD4 (0.59)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2198026	0.86	CDC7 (0.57)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2200146	0.86	BRD4 (0.62)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2199580	0.84	BRD4 (0.41)	BRD4CDC7PARP1MEN1IKBKB
	SCHEMBL2198437	0.84	BRD4 (0.42)	BRD4CDC7CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.