Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438732 | 0.98 | ACLY (0.49) | ACLYACACBACACAPPARACYP4F2 | |
| SCHEMBL8057594 | 0.98 | ACLY (0.49) | ACLYACACBACACAPPARACYP4F2 | |
| SCHEMBL20375533 | 0.93 | CYP4F2 (0.43) | ACLYACACBACACAPPARACYP4F2 | |
| SCHEMBL5527551 | 0.91 | CYP4F2 (0.46) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6256870 | 0.91 | CYP4F2 (0.42) | ACLYACACBACACACYP4F2CYP4A11 | |
| Gemcabene SCHEMBL761631 | 0.89 | ACLY (0.55) | ACLYACACBACACAPPARACYP4F2 | |
| Gemcabene SCHEMBL528316 | 0.87 | ACLY (0.53) | ACLYACACBACACAPPARACYP4F2 | |
| Gemcabene SCHEMBL4184554 | 0.87 | ACLY (0.53) | ACLYACACBACACAPPARACYP4F2 | |
| SCHEMBL5531453 | 0.87 | ACLY (0.59) | ACLYACACBACACAPPARACYP4F2 | |
| SCHEMBL6258161 | 0.87 | ACLY (0.53) | ACLYACACBACACAPPARACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653598-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING , -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS | Gemphire Therapeutics Inc. (US) | 2020-05-20 | — | — | EP | disclosed |