SCHEMBL2201689

SCHEMBL2201689

COCc1nnc(N)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7444937 0.78 POLB (0.64)
SCHEMBL1673188 0.78 POLB (0.64)
SCHEMBL12186869 0.77 POLB (0.62)
SCHEMBL3323612 0.74
SCHEMBL12500041 0.74
SCHEMBL17079275 0.74 POLB (0.59)
SCHEMBL3738440 0.74 ALDH1A1 (0.72)
SCHEMBL25153555 0.74 POLB (0.58)
SCHEMBL11787569 0.74 POLB (0.58)
SCHEMBL94109 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119144964-B Semiconductor chip post-CMP cleaning solution, and preparation method and application thereof 大连奥首科技有限公司 2025-04-08 CN claimed
CN-119144964-A Semiconductor chip post-CMP cleaning solution, and preparation method and application thereof 大连奥首科技有限公司 2024-12-17 CN claimed
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-29 US disclosed
US-12448396-B2 Methods of using heterocyclic compounds as Delta-5 Desaturase inhibitors AMGEN INC. (US) 2025-10-21 US disclosed
CN-120077028-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2025-05-30 CN disclosed
EP-4554938-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 EP disclosed
CN-119894879-A Tyrosine kinase 2 inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-25 CN disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
CN-119144964-B Semiconductor chip post-CMP cleaning solution, and preparation method and application thereof 大连奥首科技有限公司 2025-04-08 CN disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
CN-119144964-A Semiconductor chip post-CMP cleaning solution, and preparation method and application thereof 大连奥首科技有限公司 2024-12-17 CN disclosed
WO-2008078091-A1 BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS ASTEX THERAPEUTICS LIMITED (GB) 2008-07-03 WO disclosed
US-4317829-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1982-03-02 US disclosed
US-4284640-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-08-18 US disclosed
US-4277485-A INHIBITORS OF GASTRIC ACID SECRETION SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-07-07 US disclosed
US-4220652-A INHIBITORS OF H-2 HISTAMINE RECEPTORS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-09-02 US disclosed
US-4153704-A HETEROCYCLIC-ALKYL-AMINO SUBSTITUTED, ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-05-08 US disclosed
US-4124717-A INHIBITORS OF H-2 HISTAMINE RECEPTORS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1978-11-07 US disclosed
US-4080459-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1978-03-21 US disclosed
US-4013769-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-03-22 US disclosed