SCHEMBL220169

SCHEMBL220169

C=Cc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.51
PTPN1 P18031 5/20 0.47
PTPN2 P17706 2/20 0.47
PTPN6 P29350 2/20 0.47
HNF4A P41235 1/20 0.43
HSD17B10 Q99714 3/20 0.42
CDC25A P30304 1/20 0.42
CDC25B P30305 1/20 0.42
ALDH1A1 P00352 5/20 0.42
ALOX15 P16050 1/20 0.42
CYP1A2 P05177 1/20 0.42
PTGS2 P35354 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
MEN1 O00255 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL28827550 0.92 MCL1 (0.54) MCL1PTPN1PTPN2PTPN6HNF4A
SCHEMBL27643816 0.88 MCL1 (0.47) MCL1PTPN1PTPN2PTPN6HNF4A
SCHEMBL23099012 0.88 MCL1 (0.47) MCL1PTPN1PTPN2PTPN6HNF4A
SCHEMBL12339911 0.88 MCL1 (0.47) MCL1PTPN1PTPN2PTPN6HNF4A
SCHEMBL940632 0.86 MCL1 (0.48) MCL1PTPN1PTPN2PTPN6HSD17B10
SCHEMBL5467266 0.84 AKR1C3 (0.56) MCL1PTPN1HNF4AHSD17B10CDC25A
SCHEMBL20814166 0.84 MCL1 (0.47) MCL1PTPN1PTPN2PTPN6HNF4A
SCHEMBL28023538 0.84 MCL1 (0.47) MCL1PTPN1PTPN2PTPN6HSD17B10
SCHEMBL13927042 0.83 ALDH1A1 (0.47) MCL1ALDH1A1CYP1A2MEN1CYP2C9
SCHEMBL13926964 0.83 ALDH1A1 (0.51) MCL1ALDH1A1CYP1A2TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 788 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023245777-A1 HETEROGENEOUS CATALYST FOR PRODUCING VULCANIZATION ACCELERATOR TBBS BY MEANS OF OXYGEN METHOD, AND PREPARATION METHOD FOR HETEROGENEOUS CATALYST AND USE THEREOF 科迈化工股份有限公司 2023-12-28 WO claimed
EP-3720597-B1 MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES STICHTING TECHNISCHE WETENSCHAPPEN (NL) 2023-11-29 EP claimed
US-11612877-B2 Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2023-03-28 US claimed
CN-114768882-B Heterogeneous catalyst for producing vulcanization accelerator TBBS by oxygen method and preparation method and application thereof 科迈化工股份有限公司 2022-09-30 CN claimed
CN-114828648-A Pet food compositions 希尔氏宠物营养品公司 2022-07-29 CN claimed
CN-114768882-A Heterogeneous catalyst for producing vulcanization accelerator TBBS by oxygen method and preparation method and application thereof 科迈(天津)建设工程股份有限公司 2022-07-22 CN claimed
US-20200368721-A1 Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2020-11-26 US claimed
EP-3720597-A1 MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF Stichting voor de Technische Wetenschappen (NL) 2020-10-14 EP claimed
WO-2019110557-A1 MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2019-06-13 WO claimed
EP-0924102-B1 A method for lithographic printing by use of a lithographic printing plate provided by a heat sensitive non-ablatable wasteless imaging element and a fountain containing water-insoluble compounds AGFA GEVAERT (BE) 2003-07-02 EP claimed
EP-0924065-B1 A heat sensitive non-ablatable wasteless imaging element for providing a lithographic printing plate AGFA GEVAERT (BE) 2003-05-14 EP claimed
US-6306572-B1 FILM FORMING POLYMER CONTAINING CARBOXYLIC ACID OR ANHYDRIDE AGFA-GEVAERT (BE) 2001-10-23 US claimed
CN-1067992-C Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 2001-07-04 CN claimed
US-6165679-A Heat-sensitive non-ablatable wasteless imaging element for providing a lithographic printing plate AGFA-GEVAERT, N.V. (BE) 2000-12-26 US claimed
US-6165691-A Method for lithographic printing by use of a lithographic printing plate provided by a heat sensitive non-ablatable wasteless imaging element and a fountain containing water-insoluble compounds AGFA-GEVAERT, N.V. (BE) 2000-12-26 US claimed
EP-0924065-A1 A heat sensitive non-ablatable wasteless imaging element for providing a lithographic printing plate AGFA-GEVAERT N.V. (BE) 1999-06-23 EP claimed
EP-0924102-A1 A method for lithographic printing by use of a lithographic printing plate provided by a heat sensitive non-ablatable wasteless imaging element and a fountain containing water-insoluble compounds AGFA-GEVAERT N.V. (BE) 1999-06-23 EP claimed
CN-1184105-A Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 1998-06-10 CN claimed
CN-1037842-C Substituted thiazolidine derivatives, pharmaceutical compositions and uses thereof OTSUKA PHARMA CO LTD (JP) 1998-03-25 CN claimed
CN-1106982-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1995-08-16 CN claimed