Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 12/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200610 | 0.86 | MAPK14 (0.72) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6095607 | 0.84 | MAPK14 (0.72) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6095615 | 0.84 | MAPK14 (0.72) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL2201704 | 0.83 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL2201708 | 0.83 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL2198875 | 0.78 | MAPK14 (0.53) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6817357 | 0.76 | MAPK14 (0.58) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL6817158 | 0.76 | MAPK14 (0.69) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL6094761 | 0.75 | MAPK14 (0.66) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL6094767 | 0.75 | MAPK14 (0.66) | MAPK13MAPK12MAPK11MAPK14MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | MAPK13 1063/4885MAPK12 955/4885MAPK11 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.