Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.62 |
| ▸ | BRAF | P15056 | 9/20 | 0.61 |
| ▸ | EGFR | P00533 | 8/20 | 0.61 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018091 | 0.97 | KIT (0.61) | KITBRAFEGFRRETABL1 | |
| SCHEMBL22017245 | 0.87 | KIT (0.65) | KITBRAFEGFRRETABL1 | |
| SCHEMBL22018092 | 0.87 | BRAF (0.60) | KITBRAFEGFRABL1 | |
| SCHEMBL22017401 | 0.87 | TMPRSS2 (0.68) | KITBRAFEGFRRETABL1 | |
| SCHEMBL22018087 | 0.86 | TMPRSS2 (0.54) | KITBRAFEGFRRET | |
| SCHEMBL22017757 | 0.85 | TMPRSS2 (0.67) | KITBRAFEGFRRETABL1 | |
| SCHEMBL22018093 | 0.85 | BRAF (0.59) | KITBRAFEGFRABL1 | |
| SCHEMBL22017407 | 0.84 | TMPRSS2 (0.66) | KITBRAFEGFRRETABL1 | |
| SCHEMBL4254627 | 0.84 | KIT (0.79) | KITBRAFEGFRABL1 | |
| SCHEMBL22017239 | 0.84 | TMPRSS2 (0.70) | KITBRAFEGFRRETABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |