Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.60 |
| ▸ | EGFR | P00533 | 12/20 | 0.59 |
| ▸ | KIT | P10721 | 3/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018093 | 0.98 | BRAF (0.59) | BRAFEGFRKITABL1CSF1R | |
| SCHEMBL22017772 | 0.90 | BRAF (0.64) | BRAFEGFRKITABL1 | |
| SCHEMBL22017247 | 0.88 | BRAF (0.62) | BRAFEGFRKITABL1CSF1R | |
| SCHEMBL22017588 | 0.88 | TMPRSS2 (0.64) | BRAFEGFRABL1 | |
| SCHEMBL22017241 | 0.87 | KIT (0.62) | BRAFEGFRKITABL1 | |
| SCHEMBL22018091 | 0.85 | KIT (0.61) | BRAFEGFRKITABL1 | |
| SCHEMBL22017401 | 0.84 | TMPRSS2 (0.68) | BRAFEGFRKITABL1 | |
| SCHEMBL22017395 | 0.82 | EGFR (0.49) | BRAFEGFRKITABL1 | |
| SCHEMBL22017757 | 0.82 | TMPRSS2 (0.67) | BRAFEGFRKITABL1 | |
| SCHEMBL22017239 | 0.81 | TMPRSS2 (0.70) | BRAFEGFRKITABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |