Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | KIF5B | P33176 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017401 | 0.91 | TMPRSS2 (0.68) | TMPRSS2MAPTABL1BRAFRET | |
| SCHEMBL22017757 | 0.88 | TMPRSS2 (0.67) | TMPRSS2MAPTABL1BRAFRET | |
| SCHEMBL22017407 | 0.88 | TMPRSS2 (0.66) | TMPRSS2MAPTABL1BRAFRET | |
| SCHEMBL22017239 | 0.88 | TMPRSS2 (0.70) | TMPRSS2MAPTABL1BRAFRET | |
| SCHEMBL22017753 | 0.86 | TMPRSS2 (0.87) | TMPRSS2MAPTALDH1A1ABL1BRAF | |
| SCHEMBL22017408 | 0.86 | TMPRSS2 (0.79) | TMPRSS2ABL1BRAFBCRRET | |
| SCHEMBL28070242 | 0.84 | KIT (0.60) | TMPRSS2MAPTALDH1A1ABL1BRAF | |
| SCHEMBL22018089 | 0.84 | TMPRSS2 (0.68) | TMPRSS2MAPTABL1BRAFRET | |
| SCHEMBL22017590 | 0.83 | TMPRSS2 (0.68) | TMPRSS2MAPTABL1BRAFRET | |
| SCHEMBL22017586 | 0.81 | TMPRSS2 (0.57) | TMPRSS2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |